LED Inverted fluorescent microscope is composed of Epi-fluorescent microscope and inverted microscope, equipped with excellent UIS optical system and adopted long working distance plan achromatic objectives and wide field eyepieces. Compact and steady main body represents the request of anti-shake during in the operation of observation, the condenser system can be rotary move is make sure the high culture dish not be tainted during the cell of view. The Epi-fluorescence microscope system is designed with modularization function notion, so it can be safely and quickly adjust the fluorescence illuminating system and switching-over fluorescence filters. The Inverted fluorescent microscope is suitable for the field of fluorescence observation, such as cell tissue, transmitted liquid tissue, the biological pharmacy, medicine checking and measure and disease prevent.